Imaging the penumbra: strategies to detect tissue at risk after ischemic stroke

Title: Imaging the penumbra: strategies to detect tissue at risk after ischemic stroke
Creator: Ebinger, M.; De Silva, D. A.; Christensen, S.; Parsons, M. W.; Markus, R.; Donnan, G. A.; Davis, S. M.
Relation: Journal of Clinical Neuroscience Vol. 16, Issue 2, p. 178-187
Publisher Link: http://dx.doi.org/10.1016/j.jocn.2008.04.002
Publisher: Elsevier
Resource Type: journal article
Date: 2009
Description: The aim of thrombolytic therapy after acute ischemic stroke is salvage of the ischemic penumbra. Several imaging techniques have been used to identify the penumbra in patients who may benefit from reperfusion beyond the currently narrow 3-hour time-window for thrombolysis. We discuss the advantages and disadvantages of positron emission tomography (PET), single photon emission computed tomography (SPECT), MRI and CT scans. We comment on concepts of clinical-imaging mismatch models and we explore the implications for clinical trials.
Subject: penumbra; stroke; PET; SPECT; MRI; CT; clinical-diffusion mismatch
Identifier: http://hdl.handle.net/1959.13/916364
Identifier: uon:7969
Identifier: ISSN:0967-5868
Language: eng
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