Clinical relevance of brown snake (Pseudonaja spp) factor V escaping hemostatic regulation (letter)

Title: Clinical relevance of brown snake (Pseudonaja spp) factor V escaping hemostatic regulation (letter)
Creator: Isbister, Geoffrey K.; Scorgie, Fiona E.; Seldon, Michael; Lincz, Lisa F.
Relation: Blood Vol. 114, Issue 12, p. 2563-2564
Publisher Link: http://dx.doi.org/10.1182/blood-2009-07-229716
Publisher: American Society of Hematology
Resource Type: journal article
Date: 2009
Description: Despite the work by Bos et al. reported in Blood and by other researchers on the structure and function of the procoagulant molecules, the pathophysiology of venom-induced consumption coagulopathy (VICC) associated with human envenoming by these snakes remains unclear. Although it would appear that the presence of a factor Va–like toxin in brown snake (Pseudonaja spp) venom that is impervious to regulation by the hemostatic system provides a potent biologic weapon against prey and in human envenoming, clinical research does not fully support this.
Subject: venom-induced consumption coagulopathy (VICC); human envenoming; brown snake venom; Pseudonaja spp; hemostatic regulation
Identifier: http://hdl.handle.net/1959.13/807206
Identifier: uon:7335
Identifier: ISSN:0006-4971
Language: eng

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