- Title
- Collateral assessment on magnetic resonance imaging/angiography up to 30 hours after stroke onset
- Creator
- Tomari, Shinya; Lillicrap, Thomas; Garcia-Esperon, Carlos; Kashida, Yumi Tomari; Bivard, Andrew; Lin, Longting; Levi, Christopher R.; Spratt, Neil J.
- Relation
- PLoS One Vol. 19, Issue 9, no. e0309779
- Publisher Link
- http://dx.doi.org/10.1371/journal.pone.0309779
- Publisher
- Public Library of Science (PLOS)
- Resource Type
- journal article
- Date
- 2024
- Description
- Purpose: We aimed to validate hyperintense vessel sign (HVS) on FLAIR imaging or posterior cerebral artery (PCA) laterality on MR angiography beyond 4.5 hours after stroke onset. Materials and methods: Data from acute ischemic stroke patients with internal carotid or middle cerebral artery occlusion who underwent CT perfusion imaging at baseline, follow-up MR perfusion imaging and angiography within 30 hours after stroke, without effective recanalization on follow-up imaging, were analysed retrospectively. Patients were separately classified as high or low HVS (>5 or ≤5 slices of HVS), and PCA laterality positive or negative group. We compared core and penumbra volumes at follow-up imaging and neurological outcomes between high or low HVS group, and between PCA laterality positive or negative group. Results: Of 49 patients analyzed, four patients with artifacts were excluded and 45 were classified into high (n = 23) or low (n = 22) HVS group. High group had a smaller core volume (median 32 ml versus 109 ml, p = 0.004), larger penumbra volume at follow-up (68 ml versus 0 ml, p = 0.001), and better outcomes (modified Rankin Scale at three months, 3 versus 5, p = 0.03). For PCA laterality analysis, 1 patient with previously occluded PCA was excluded and 48 patients were classified as positive (n = 22) or negative (n = 26). Positive group had larger core volume (116 ml versus 37 ml), and no significant differences in penumbral volumes or outcomes. Conclusion: Prominent HVS in later time was associated with small core volume, persistent penumbra volume and favorable outcomes.
- Subject
- ischemic stroke; neuroimaging; angiography; cerebral arteries; SDG 3; Sustainable Development Goal
- Identifier
- http://hdl.handle.net/1959.13/1517363
- Identifier
- uon:57081
- Identifier
- ISSN:1932-6203
- Rights
- x
- Language
- eng
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