Targeted Therapies for Microvascular Disease

Title: Targeted Therapies for Microvascular Disease
Creator: Bland, Adam; Chuah, Eunice; Meere, William; Ford, Thomas J.
Relation: Cardiology Clinics Vol. 42, Issue 1, p. 137-145
Publisher Link: http://dx.doi.org/10.1016/j.ccl.2023.07.002
Publisher: Elsevier
Resource Type: journal article
Date: 2024
Description: Coronary microvascular dysfunction (CMD) is a common cause of ischemia but no obstructive coronary artery disease that results in an inability of the coronary microvasculature to meet myocardial oxygen demand. CMD is challenging to diagnose and manage due to a lack of mechanistic research and targeted therapy. Recent evidence suggests we can improved patient outcomes by stratifying antianginal therapies according to the diagnosis revealed by invasive assessment of the coronary microcirculation. This review article appraises the evidence for management of CMD, which includes treatment of cardiovascular risk, antianginal therapy and therapy for atherosclerosis.
Subject: angina; coronary microvascular dysfunction (CMD); ischemia but no obstructive coronary artery disease (INOCA); ischemia; management
Identifier: http://hdl.handle.net/1959.13/1494738
Identifier: uon:53868
Identifier: ISSN:0733-8651
Language: eng
Reviewed

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