- Title
- The relationship between fermentable carbohydrates and post-prandial bowel symptoms in patients with functional bowel disorders
- Creator
- MacIntosh, Alice; Heenan, Phoebe E.; Wright-McNaughton, Morag; Frampton, Chris; Skidmore, Paula; Wall, Catherine L.; Muir, Jane; Talley, Nicholas Joseph; Roy, Nicole Clemence; Gearry, Richard B.
- Relation
- Frontiers in Nutrition Vol. 10, no. 1060928
- Publisher Link
- http://dx.doi.org/10.3389/fnut.2023.1060928
- Publisher
- Frontiers Research Foundation
- Resource Type
- journal article
- Date
- 2023
- Description
- Background and aims: A low fermentable oligosaccharide, disaccharide, monosaccharide, and polyols (FODMAP) diet alleviates symptoms of irritable bowel syndrome (IBS). We aimed to investigate the relationship between habitual FODMAP intake and post-prandial bowel symptoms in adults with IBS, functional diarrhoea (FD), or constipation (FD) (functional bowel disorders), and in healthy adults (controls). Methods: 292 participants (173 with functional bowel disorders and 119 controls) completed a food and symptom times diary. Estimated meal portion sizes were entered into the Monash FODMAP Calculator to analyse FODMAP content. Wilcoxon and ANOVA tests were used to investigate the relationship between FODMAP intake and post-prandial bowel symptoms. Results: IBS participants experienced more post-prandial bowel symptoms compared to participants with other functional bowel disorders or controls. Meals associated with abdominal pain contained on average increased excess fructose (0.31 g vs. 0.18 g, p < 0.05), sorbitol (0.27 g vs. 0.10 g, p < 0.01), and total FODMAP (3.46 g vs. 2.96 g, p < 0.05) compared to meals not associated with pain. Abdominal swelling was associated with increased sorbitol (0.33 g vs. 0.11 g, p < 0.01), and total FODMAP (3.26 g vs. 3.02 g, p < 0.05) consumption. Abdominal bloating was associated with increased galacto oligosaccharide consumption (0.18 g vs. 0.14 g, p < 0.05). Conclusion: These findings support the role of FODMAP in post-prandial bowel symptom onset, however, the amount and type of FODMAP triggering symptoms vary between individuals. Future research should investigate the relationship between the effect of individual FODMAP consumption on post-prandial bowel symptoms for each subtype, the interaction of FODMAP with differing functional bowel disorders and whether longitudinally symptoms and dietary intake are stable.
- Subject
- FODMAP; functional bowel disorder; fiber; post-prandial bowel symptoms; diet; gastrointestinal symptom
- Identifier
- http://hdl.handle.net/1959.13/1490909
- Identifier
- uon:53012
- Identifier
- ISSN:2296-861X
- Rights
- © 2023 MacIntosh, Heenan, Wright-McNaughton, Frampton, Skidmore, Wall, Muir, Talley, Roy and Gearry. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Language
- eng
- Full Text
- Reviewed
- Hits: 2843
- Visitors: 2920
- Downloads: 82
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 588 KB | Adobe Acrobat PDF | View Details Download |