- Title
- Pre-exercise carbohydrate status influences carbohydrate-mediated attenuation of post-exercise cytokine responses
- Creator
- Cox, A. J.; Pyne, D. B.; Cox, G. R.; Callister, R.; Gleeson, M.
- Relation
- International Journal of Sports Medicine Vol. 29, Issue 12, p. 1003-1009
- Publisher Link
- http://dx.doi.org/10.1055/s-2008-1038753
- Publisher
- Georg Thieme
- Resource Type
- journal article
- Date
- 2008
- Description
- Most studies investigating the effects of acute carbohydrate (CHO) ingestion on post-exercise cytokine responses have involved fasted athletes. This study characterised the effects of acute CHO beverage ingestion preceded by consumption of a CHO-containing pre-exercise meal. Sixteen highly-trained male cyclists/triathletes (age: 30.6 ± 5.6 y; VO₂max: 64.8 ± 4.7 ml kg min⁻¹ [mean ± SD]) undertook two cycle ergometry trials involving randomised consumption of a 10 % CHO beverage (15 mL kg⁻¹ hr⁻¹) or water (H₂O). Trials were undertaken 2 h after a breakfast providing 2.1 g CHO kg⁻¹ body mass (BM) (48 kJ kg⁻¹ BM) and consisted of 100 min steady state cycle ergometry at 70 % VO₂max followed by a time trial of ~ 30 min duration. Blood samples were collected pre-, post- and 1 h post-exercise for measurement of Interleukin (IL)-6, IL-8, IL-10 and IL-1ra. Time-trial performance was not substantially different between CHO and H₂O trials (4.5 %, p = 0.42). Neither IL-6 nor IL-8 responses were substantially reduced in the CHO compared to the H₂O trial. There was a substantial reduction in IL-10 (32 %, p = 0.05) and IL-1ra (43 %, p = 0.02) responses at 1 h post-exercise with CHO compared to H₂O ingestion. In conclusion, the previously shown attenuating effects of CHO ingestion during exercise on cytokine responses appear reduced when athletes consume a CHO-containing pre-exercise meal.
- Subject
- immunity; carbohydrates; athletes; exercise
- Identifier
- uon:5251
- Identifier
- http://hdl.handle.net/1959.13/43123
- Identifier
- ISSN:0172-4622
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