Acitretin for lichen amyloidosus

Title: Acitretin for lichen amyloidosus
Creator: Choi, James Y. J.; Sippe, John; Lee, Stephen
Relation: Australasian Journal of Dermatology Vol. 49, Issue 2, p. 109-113
Relation: http://www3.interscience.wiley.com/journal/119387876/abstract
Publisher: Wiley Interscience
Resource Type: journal article
Date: 2008
Description: We present two cases of lichen amyloidosus treated with retinoids. A 57-year-old Vietnamese woman has had extensive generalized recalcitrant lichen amyloidosus for 23 years. Treatment with oral etretinate (25 mg/day) for 3 years, and later oral acitretin (10 mg/day) for the past 10 years, has controlled the pruritus and flattened the hyperkeratotic papules. Whenever the acitretin was ceased her symptoms flared within weeks. On each occasion reintroduction of acitretin was effective within 1-2 months. The second case is that of a 51-year-old Australian Aboriginal woman who had a 2-year history of lichen amyloidosus affecting her lower legs. A 2-month course of oral acitretin (25 mg b.d.) produced a marked improvement in both the pruritus and hyperkeratotic papules. She was then lost to follow up for 2 years, during which time her symptoms recurred.
Subject: amyloid; Australian Aborigine; etretinate; primary cutaneous amyloid; retinoid; Vietnamese
Identifier: uon:5235
Identifier: http://hdl.handle.net/1959.13/43107
Identifier: ISSN:1440-0960

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