- Title
- The C3 conundrum
- Creator
- Lean, Maria; Chacko, Bobby
- Relation
- Internal Medicine Journal Vol. 53, Issue 6, p. 1065-1069
- Publisher Link
- http://dx.doi.org/10.1111/imj.16111
- Publisher
- John Wiley & Sons
- Resource Type
- journal article
- Date
- 2023
- Description
- A 62-year-old man with nephritic syndrome underwent a kidney biopsy which revealed a C3 dominant pattern on immunofluorescence. A diagnosis of C3 glomerulopathy (C3G) was suspected. However, a recent skin infection and high levels of anti-streptococcal antibodies were indicative of post-infectious glomerulonephritis (PIGN). This paper compares PIGN and C3G and describes an atypical form of PIGN with alternative complement pathway dysregulation.
- Subject
- acute glomerulonephritis; C3 glomerulopathy (C3G); post-infectious glomerulonephritis (PIGN); kidney failure
- Identifier
- http://hdl.handle.net/1959.13/1487842
- Identifier
- uon:52267
- Identifier
- ISSN:1444-0903
- Rights
- x
- Language
- eng
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