Effect of activated charcoal on citalopram-induced QT prolongation: reply (letter)

Title: Effect of activated charcoal on citalopram-induced QT prolongation: reply (letter)
Creator: Isbister, Geoffrey K.; Stokes, Barrie; Buckle, Nicholas A.; Duffull, Stephen B.
Relation: Annals of Emergency Medicine Vol. 52, Issue 1, p. 87-88
Publisher Link: http://dx.doi.org/10.1016/j.annemergmed.2007.11.046
Publisher: American College of Emergency Physicians
Resource Type: journal article
Date: 2008
Description: We thank Greene et al for their comments on our study of citalopram overdoses. They raise a number of issues about the study that we can clarify. We agree that it is difficult to determine how useful QT prolongation is as a predictor of citalopram-induced cardiotoxicity. However, Torsades de Pointes (TdP) has been reported in citalopram overdose and there is a well-known association between QT prolongation and malignant arrhythmias. We have recently shown that the QT nomogram used in our study is a valid approach to assessing an abnormal QT interval and risk of Torsades de Pointes.
Subject: citalopram overdoses; charcoal; clinical toxicology; treatments
Identifier: uon:5173
Identifier: http://hdl.handle.net/1959.13/43039
Identifier: ISSN:0196-0644

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