- Title
- A Comprehensive Review on the Techniques for Extraction of Bioactive Compounds from Medicinal Cannabis
- Creator
- AL Ubeed, Hebah Muhsien Sabiah; Bhuyan, Deep Jyoti; Alsherbiny, Muhammad A.; Basu, Amrita; Vuong, Quan V.
- Relation
- Molecules Vol. 27, Issue 3, no. 604
- Publisher Link
- http://dx.doi.org/10.3390/molecules27030604
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2022
- Description
- Cannabis is well-known for its numerous therapeutic activities, as demonstrated in pre-clinical and clinical studies primarily due to its bioactive compounds. The Cannabis industry is rapidly growing; therefore, product development and extraction methods have become crucial aspects of Cannabis research. The evaluation of the current extraction methods implemented in the Cannabis industry and scientific literature to produce consistent, reliable, and potent medicinal Cannabis extracts is prudent. Furthermore, these processes must be subjected to higher levels of scientific stringency, as Cannabis has been increasingly used for various ailments, and the Cannabis industry is receiving acceptance in different countries. We comprehensively analysed the current literature and drew a critical summary of the extraction methods implemented thus far to recover bioactive compounds from medicinal Cannabis. Moreover, this review outlines the major bioactive compounds in Cannabis, discusses critical factors affecting extraction yields, and proposes future considerations for the effective extraction of bioactive compounds from Cannabis. Overall, research on medicinal marijuana is limited, with most reports on the industrial hemp variety of Cannabis or pure isolates. We also propose the development of sustainable Cannabis extraction methods through the implementation of mathematical prediction models in future studies.
- Subject
- cannabis; medicinal cannabis; cannabinoids; extraction methods; SDG 9; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1480907
- Identifier
- uon:50589
- Identifier
- ISSN:1420-3049
- Rights
- © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- Language
- eng
- Full Text
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