- Title
- Selective cutoff reporting in studies of the accuracy of the Patient Health Questionnaire-9 and Edinburgh Postnatal Depression Scale: Comparison of results based on published cutoffs versus all cutoffs using individual participant data meta-analysis
- Creator
- Neupane, Dipika; Levis, Brooke; Bhandari, Parash M.; Thombs, Brett D.; Benedetti, Andrea; DEPRESsion Screening Data (DEPRESSD) Collaboration; Sun, Ying; He, Chen; Wu, Yin; Krishnan, Ankur; Negeri, Zelalem; Imran, Mahrukh; Rice, Danielle B.; Riehm, Kira E.; Saadat, Nazanin; Azar, Marleine; Sanchez, Tatiana A.; Chiovitti, Matthew J.; Levis, Alexander W.; Boruff, Jill T.; Cuijpers, Pim; Gilbody, Simon; Ioannidis, JPA; Kloda, LA; Patten, SB; Shrier, I; Ziegelstein, RC; Comeau, L; Mitchell, ND; Tonelli, M; Vigod, SN; Akena, DH; Alvarado, R; Arroll, B; Bakare, MO; Baradaran, HR; Beck, CT; Bombardier, CH; Bunevicius, A; Carter, Gregory; Chagas, MH; Chaudron, LH; Cholera, R; Clover, Kerrie; Conwell, Y; Castro e Couto, T; de Man-van Ginkel, JM; Delgadillo, J; Fann, JR; Favez, N; Fung, D; Garcia-Esteve, L; Gelaye, B; Goodyear-Smith, F; Hyphantis, T; Inagaki, M; Ismail, K; Jetté, N; Khalifa, DS; Khamseh, ME; Kohlhoff, J; Kozinszky, Z; Kusminskas, L; Liu, SI; Lotrakul, M; Loureiro, SR; Löwe, B; Sidik, SM; Nakić Radoš, S; Osório, FL; Pawlby, SJ; Pence, BW; Rochat, TJ; Rooney, AG; Sharp, DJ; Stafford, L; Su, KP; Sung, SC; Tadinac, M; Darius Tandon, S; Thiagayson, P; Töreki, A; Torres-Giménez, A; Turner, Alyna; van der Feltz-Cornelis, CM; Vega-Dienstmaier, JM; Vöhringer, PA; White, J; Whooley, MA; Winkley, K; Yamada, M
- Relation
- International Journal of Methods in Psychiatric Research Vol. 30, Issue 3, no. e1873
- Publisher Link
- http://dx.doi.org/10.1002/mpr.1873
- Publisher
- John Wiley & Sons
- Resource Type
- journal article
- Date
- 2021
- Description
- Objectives: Selectively reported results from only well-performing cutoffs in diagnostic accuracy studies may bias estimates in meta-analyses. We investigated cutoff reporting patterns for the Patient Health Questionnaire-9 (PHQ-9; standard cutoff 10) and Edinburgh Postnatal Depression Scale (EPDS; no standard cutoff, commonly used 10–13) and compared accuracy estimates based on published cutoffs versus all cutoffs. Methods: We conducted bivariate random effects meta-analyses using individual participant data to compare accuracy from published versus all cutoffs. Results: For the PHQ-9 (30 studies, N = 11,773), published results underestimated sensitivity for cutoffs below 10 (median difference: −0.06) and overestimated for cutoffs above 10 (median difference: 0.07). EPDS (19 studies, N = 3637) sensitivity estimates from published results were similar for cutoffs below 10 (median difference: 0.00) but higher for cutoffs above 13 (median difference: 0.14). Specificity estimates from published and all cutoffs were similar for both tools. The mean cutoff of all reported cutoffs in PHQ-9 studies with optimal cutoff below 10 was 8.8 compared to 11.8 for those with optimal cutoffs above 10. Mean for EPDS studies with optimal cutoffs below 10 was 9.9 compared to 11.8 for those with optimal cutoffs greater than 10. Conclusion: Selective cutoff reporting was more pronounced for the PHQ-9 than EPDS.
- Subject
- diagnostic test accuracy; individual participant data meta-analysis; meta-analysis; publication bias; selective cutoff reporting
- Identifier
- http://hdl.handle.net/1959.13/1476931
- Identifier
- uon:49889
- Identifier
- ISSN:1049-8931
- Rights
- © 2021 The Authors. International Journal of Methods in Psychiatric Research published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
- Language
- eng
- Full Text
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