- Title
- A mild Boc deprotection and the importance of a free carboxylate
- Creator
- Thaqi, Ali; McCluskey, Adam; Scott, Janet L.
- Relation
- Tetrahedron Letters Vol. 49, Issue 49, p. 6962-6964
- Publisher Link
- http://dx.doi.org/10.1016/j.tetlet.2008.09.027
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2008
- Description
- We report a facile and rapid removal of Boc protecting groups using microwave heating in H₂O, with deprotection only requiring a free carboxylic acid group in the starting material. Unlike previous approaches, no additional reagents are required.
- Subject
- amino acids; peptides; free carboxylic acid group; Boc-de-protection
- Identifier
- http://hdl.handle.net/1959.13/41348
- Identifier
- uon:4735
- Identifier
- ISSN:0040-4039
- Language
- eng
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