Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD

Title: Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD
Creator: Althoff, Meghan D.; Ghincea, Alexander; Wood, Lisa G.; Holguin, Fernando; Sharma, Sunita
Relation: Journal of Allergy and Clinical Immunology: In Practice Vol. 9, Issue 11, p. 3877-3884
Publisher Link: http://dx.doi.org/10.1016/j.jaip.2021.09.003
Publisher: Elsevier
Resource Type: journal article
Date: 2021
Description: Asthma is a complex disease with heterogeneous phenotypes and endotypes that are incompletely understood. Obesity, obstructive sleep apnea, and gastroesophageal reflux disease co-occur in patients with asthma at higher rates than in those without asthma. Although these diseases share risk factors, there are some data suggesting that these comorbidities have shared inflammatory pathways, drive the development of asthma, or worsen asthma control. This review discusses the epidemiology, pathophysiology, management recommendations, and key knowledge gaps of these common comorbidities.
Subject: asthma; obesity; obstructive sleep apnea; gastroesophageal reflux disease; SDG 3; Sustainable Development Goals
Identifier: http://hdl.handle.net/1959.13/1461506
Identifier: uon:46219
Identifier: ISSN:2213-2198
Language: eng
Reviewed