- Title
- Experimental evaluation of four-dimensional Magnetic Resonance Imaging for radiotherapy planning of lung cancer
- Creator
- Perkins, Terry; Lee, Danny; Simpson, John; Greer, Peter; Goodwin, Jonathan
- Relation
- Physics and Imaging in Radiation Oncology Vol. 17, Issue January 2021, p. 32-35
- Publisher Link
- http://dx.doi.org/10.1016/j.phro.2020.12.006
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2021
- Description
- Radiotherapy planning for lung cancer typically requires both 3D and 4D Computed Tomography (CT) to account for respiratory related movement. 4D Magnetic Resonance Imaging (MRI) with self-navigation offers a potential alternative with greater reliability in patients with irregular breathing patterns and improved soft tissue contrast. In this study 4D-CT and a 4D-MRI Radial Volumetric Interpolated Breath-hold Examination (VIBE) sequence was evaluated with a 4D phantom and 13 patient respiratory patterns, simulating tumour motion. Quantification of motion related tumour displacement in 4D-MRI and 4D-CT found no statistically significant difference in mean motion range. The results demonstrated the potential viability of 4D-MRI for lung cancer treatment planning.
- Subject
- 4D-CT; 4D-MRI; lung cancer; radial VIBE; self-navigating; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1456884
- Identifier
- uon:45273
- Identifier
- ISSN:2405-6316
- Rights
- © 2021 The Authors. Published by Elsevier B.V. on behalf of European Society of Radiotherapy & Oncology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
- Language
- eng
- Full Text
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