- Title
- Optimising Cardiometabolic Risk Factors in Pregnancy: A Review of Risk Prediction Models Targeting Gestational Diabetes and Hypertensive Disorders
- Creator
- Thong, Eleanor P.; Ghelani, Drishti P.; Harrison, Cheryce L.; Moran, Lisa; Enticott, Joanne; Manoleehakul, Pamada; Yesmin, Anika; Slater, Kaylee; Taylor, Rachael; Collins, Clare; Hutchesson, Melinda; Lim, Siew S.; Teede, Helena J.
- Relation
- Journal of Cardiovascular Development and Disease Vol. 9, Issue 2, no. 55
- Publisher Link
- http://dx.doi.org/10.3390/jcdd9020055
- Publisher
- MDPI AG
- Resource Type
- journal article
- Date
- 2022
- Description
- Cardiovascular disease, especially coronary heart disease and cerebrovascular disease, is a leading cause of mortality and morbidity in women globally. The development of cardiometabolic conditions in pregnancy, such as gestational diabetes mellitus and hypertensive disorders of pregnancy, portend an increased risk of future cardiovascular disease in women. Pregnancy therefore represents a unique opportunity to detect and manage risk factors, prior to the development of cardiovascular sequelae. Risk prediction models for gestational diabetes mellitus and hypertensive disorders of pregnancy can help identify at-risk women in early pregnancy, allowing timely intervention to mitigate both short- and long-term adverse outcomes. In this narrative review, we outline the shared pathophysiological pathways for gestational diabetes mellitus and hypertensive disorders of pregnancy, summarise contemporary risk prediction models and candidate predictors for these conditions, and discuss the utility of these models in clinical application.
- Subject
- cardiovascular; risk prediction; pregnancy; gestational diabetes; hypertensive disorders of pregnancy; preeclampsia; SDG 3; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1456514
- Identifier
- uon:45227
- Identifier
- ISSN:2308-3425
- Rights
- This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/
- Language
- eng
- Full Text
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