What inotrope and why?

Title: What inotrope and why?
Creator: Phad, Nilkant; de Waal, Koert
Relation: Clinics in Perinatology Vol. 47, Issue 3, p. 529-547
Publisher Link: http://dx.doi.org/10.1016/j.clp.2020.05.010
Publisher: Elsevier
Resource Type: journal article
Date: 2020
Description: Primary function of cardiovascular system is to meet body's metabolic demands. The aim of inotrope therapy is to minimise adverse impact of cardiovascular compromise. Current use of inotropes is primarily guided by the pathophysiology of cardiovascular compromise and anticipated actions of inotropes. Lack of significant reduction in morbidity and mortality associated with cardiovascular compromise despite inotrope use, highlights major gaps in our understanding of circulatory targets, thresholds and choices of inotrope therapy. Thus far, prevention of cardiovascular compromise remains the most effective strategy to optimize outcomes. Studies of alternative design are needed for further advancement in cardiovascular therapy in neonates.
Subject: hypotension; cardiovascular compromise; inotrope; newborn
Identifier: http://hdl.handle.net/1959.13/1451240
Identifier: uon:44135
Identifier: ISSN:0095-5108
Language: eng
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