- Title
- Acute effects of frequent light-intensity standing-based exercises that interrupt 8 hours of prolonged sitting on postprandial glucose in stroke survivors: a dose-escalation trial
- Creator
- Mackie, Paul; Crowfoot, Gary; Gyawali, Prajwal; Janssen, Heidi; Holliday, Elizabeth; Dunstan, David; English, Coralie
- Relation
- Journal of Physical Activity and Health Vol. 18, Issue 6, p. 644-652
- Publisher Link
- http://dx.doi.org/10.1123/jpah.2020-0516
- Publisher
- Human Kinetics
- Resource Type
- journal article
- Date
- 2021
- Description
- Background: Interrupting prolonged sitting can attenuate postprandial glucose responses in overweight adults. The dose–response effect in stroke survivors is unknown. The authors investigated the effects of interrupting 8 hours of prolonged sitting with increasingly frequent bouts of light-intensity standing-based exercises on the postprandial glucose response in stroke survivors. Methods: Within-participant, laboratory-based, dose-escalation trial. Participants completed three 8-hour conditions: prolonged sitting and 2 experimental conditions. Experimental conditions involved light-intensity standing-based exercises of increasing frequency (2 × 5 min to 6 × 5 min bouts). Postprandial glucose is reported. Results: Twenty-nine stroke survivors (aged 66 y) participated. Interrupting 8 hours of prolonged sitting with light-intensity standing-based exercises every 90 minutes significantly decreased postprandial glucose (positive incremental area under the curve; −1.1 mmol/L·7 h; 95% confidence interval, −2.0 to −0.1). In the morning (08:00–11:00), postprandial glucose decreased during the 4 × 5 minutes and 6 × 5 minutes conditions (positive incremental area under the curve; −0.8 mmol/L·3 h; 95% confidence interval, −1.3 to −0.3 and −0.8 mmol/L·3 h; 95% confidence interval, −1.5 to −0.2, respectively) compared with prolonged sitting. Conclusion: Interrupting 8 hours of prolonged sitting at least every 90 minutes with light-intensity standing-based exercises attenuates postprandial glucose in stroke survivors. During the morning, postprandial glucose is attenuated when sitting is interrupted every 60 and 90 minutes.
- Subject
- clinical research; exercise; metabolic health
- Identifier
- http://hdl.handle.net/1959.13/1431390
- Identifier
- uon:38956
- Identifier
- ISSN:1543-3080
- Language
- eng
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