- Title
- Dietary fibre as a modulator of airway inflammation in asthma (FAIM Study)
- Creator
- Wood, Lisa; Baines, Katherine; Arnold, David; Berthon, Bronwyn; Gibson, Peter; Zapirain, Rebecca
- Resource Type
- protocol
- Description
- Soluble fibre is a source of plasma short chain fatty acids (SCFA), which are known to have anti-inflammatory properties. This study will investigate the effects of soluble fibre supplementation on asthma control and airway and systemic inflammation in clinically stable asthmatic adults. The soluble fibre inulin, will be delivered at a dose previously shown to modulate the microbiome, reduce inflammation and be well tolerated. The duration of intervention (7 days) reflects the time required to achieve maximum improvements in gut microflora and the washout period (2 weeks) is adequate to allow the microflora to return to baseline composition.
- Subject
- asthma; inulin; soluble fibre; SCFAs; free fatty acid receptors; inflammation; prebiotic; asthma treatment; dietary fibre; clinical trial
- Identifier
- http://hdl.handle.net/1959.13/1397040
- Identifier
- uon:34174
- Rights
- This work is licensed under a Creative Commons Attribution 4.0 International License.
- Language
- eng
- Full Text
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