Successful renal transplantation in a patient with cold agglutinin disease

Title: Successful renal transplantation in a patient with cold agglutinin disease
Creator: Vilayur, Eswari; Trevillian, Paul; Heer, Munish
Relation: Journal of Clinical Apheresis Vol. 32, Issue 1, p. 56-58
Publisher Link: http://dx.doi.org/10.1002/jca.21460
Publisher: John Wiley & Sons
Resource Type: journal article
Date: 2017
Description: Cold agglutinin disease is a rare cause of acute graft loss after renal transplantation. A 71-year-old female with end stage renal failure was diagnosed to have cold agglutinin disease when investigated for recurrent clotting of hemodialysis circuits. Kidney transplantation was a major challenge due to unavoidable exposure of the transplant kidney to cold temperatures. Large volume plasma exchange given pre-transplant and infusion of warm saline prior to anastomosis resulted in successful renal transplantation with good graft function despite initial delayed graft function. This challenging case illustrates the complete removal of cold agglutinin antibodies with therapeutic large volume plasma exchange.
Subject: cold agglutinin disease; plasma exchange; renal transplantation
Identifier: http://hdl.handle.net/1959.13/1395961
Identifier: uon:33968
Identifier: ISSN:0733-2459
Language: eng
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