- Title
- Photobiology of vitamins
- Creator
- Lucock, Mark; Jones, Patrice; Martin, Charlotte; Yates, Zoe; Veysey, Martin; Furst, John; Beckett, Emma
- Relation
- Nutrition Reviews Vol. 76, Issue 7, p. 512-525
- Publisher Link
- http://dx.doi.org/10.1093/nutrit/nuy013
- Publisher
- Oxford University Press
- Resource Type
- journal article
- Date
- 2018
- Description
- This review explores contemporary ideas about the relationship between light exposure and vitamin biology. Nutritional biochemistry has long recognized the relationship between vitamins A and D and light exposure, but in recent years other vitamins have also been implicated in photoresponsive biological mechanisms that influence health, well-being, and even evolutionary processes. Interactions between light and vitamins can modify genotype-phenotype relationships across the life cycle, providing a basis for interesting new explanations relevant to wide aspects of human biology. This review examines both well-established and emerging ideas about vitamin photobiology in the context of the following: (1) light responsiveness of vitamin D (photosynthesized in skin), vitamin A (linked to vision), and vitamin B3 (needed to repair genomic damage); (2) vulnerability of folate and vitamins B1, B2, B12, and D to ultraviolet (UV) light (all potentially degraded); (3) protective/filtering actions of carotenoids and vitamins C and E, which act as antioxidants and/or natural sunscreens, against UV light; (4) role of folate, carotenoids, and vitamins A, B3, C, D, and E in UV-related genomic regulation, maintenance, and repair; (5) role of folate and vitamins A, B2, B12, and D in a range of light-signaling and light-transduction pathways; and (6) links between folate and vitamin D and the evolution of UV light-adaptive phenotypes.
- Subject
- molecular nutrition; photobiology; vitamins
- Identifier
- http://hdl.handle.net/1959.13/1392616
- Identifier
- uon:33435
- Identifier
- ISSN:0029-6643
- Rights
- This is a pre-copyedited, author-produced version of an article accepted for publication in the Nutrition Reviews following peer review. The version of the above record is available online at: http://dx.doi.org/10.1093/nutrit/nuy013
- Language
- eng
- Full Text
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