- Title
- Time as context: The influence of hierarchical patterning on sensory inference
- Creator
- Todd, Juanita; Petherbridge, Anne; Speirs, Bronte; Provost, Alexander; Paton, Bryan
- Relation
- Funding BodyNHMRCGrant Number1080938 http://purl.org/au-research/grants/nhmrc/1080938
- Relation
- Schizophrenia Research Vol. 191, Issue January, p. 123-131
- Publisher Link
- http://dx.doi.org/10.1016/j.schres.2017.03.033
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2018
- Description
- Time, or more specifically temporal structure, is a critical variable in understanding how the auditory system uses acoustic patterns to predict input, and to filter events based on their relevance. A key index of this filtering process is the auditory evoked potential component known as mismatch negativity or MMN. In this paper we review findings of smaller MMN in schizophrenia through the lens of time as an influential contextual variable. More specifically, we review studies that show how MMN to a locally rare pattern-deviation is modulated by the longer-term context in which it occurs. Empirical data is presented from a non-clinical sample confirming that the absence of a stable higher-order structure to sound sequences alters the way MMN amplitude changes over time. This result is discussed in relation to how hierarchical pattern learning might enrich our understanding of how and why MMN amplitude modulation is disrupted in schizophrenia.
- Subject
- mismatch negativity; temporal processing; context; hierarchical inference; predictive coding
- Identifier
- http://hdl.handle.net/1959.13/1392510
- Identifier
- uon:33406
- Identifier
- ISSN:0920-9964
- Language
- eng
- Reviewed
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