- Title
- Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: a cross-sectional study
- Creator
- Petersen, Kristina S.; Keogh, Jennifer B.; Meikle, Peter J.; Garg, Manohar L.; Clifton, Peter M.
- Relation
- Funding BodyNHMRCGrant Number1042095 http://purl.org/au-research/grants/nhmrc/1042095
- Relation
- World Journal of Diabetes Vol. 8, Issue 1, p. 18-27
- Publisher Link
- http://dx.doi.org/10.4239/wjd.v8.i1.18
- Publisher
- Baishideng Publishing Group
- Resource Type
- journal article
- Date
- 2017
- Description
- Aim: To determine the clinical and dietary predictors of common carotid artery intima media thickness (CCA IMT) in a cohort of subjects with type 1 and type 2 diabetes. Methods: Participants with type 1 (n = 23) and type 2 diabetes (n = 127) had mean and mean maximum CCA IMT measured using B mode ultrasound. Dietary intake was measured using a food frequency questionnaire. Clinical and dietary predictors of mean and mean maximum CCA IMT were determined using linear regression analysis adjusted for potential confounders. Results: The main predictors of mean and mean maximum CCA IMT were age and weight. After multivariate adjustment there were no dietary predictors of CCA IMT. However, in subjects that were not prescribed a lipid lowering medication alcohol consumption was positively associated with CCA IMT after multivariate adjustment. No difference existed in CCA IMT between subjects with type 1 or type 2 diabetes once age was adjusted for. Conclusion: CCA IMT was predominantly predicted by age and weight in these subjects with diabetes. The finding that CCA IMT was not different between people with type 1 and type 2 diabetes warrants further investigation in a larger cohort.
- Subject
- diabetes; carotid intima media thickness; arterial structure; diet; lipidomics; carotenoids
- Identifier
- http://hdl.handle.net/1959.13/1384432
- Identifier
- uon:32072
- Identifier
- ISSN:1948-9358
- Rights
- This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
- Language
- eng
- Full Text
- Reviewed
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