Repurposing some older drugs that cross the blood-brainier and have potential anticancer activity to provide new treatment options for glioblastoma

Title: Repurposing some older drugs that cross the blood-brainier and have potential anticancer activity to provide new treatment options for glioblastoma
Creator: Rundle-Thiele, Dayle; Head, Richard; Cosgrove, Leah; Martin, Jennifer H.
Relation: British Journal of Clinical Pharmacology Vol. 81, Issue 2, p. 199-209
Publisher Link: http://dx.doi.org/10.1111/bcp.12785
Publisher: Wiley-Blackwell
Resource Type: journal article
Date: 2016
Description: Glioblastoma is a brain neoplasm with limited 5-year survival rates. Developments of new treatment regimens that improve patient survival in patients with glioblastoma are needed. It is likely that a number of existing drugs used in other conditions have potential anticancer effects that offer significant survival benefit to glioblastoma patients. Identification of such drugs could provide a novel treatment paradigm.
Subject: antidepressants; antiepileptic drugs; antihypertensive; beta-blockers; glioblastoma; statins
Identifier: http://hdl.handle.net/1959.13/1320313
Identifier: uon:24125
Identifier: ISSN:0306-5251
Language: eng
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