Employment of microRNA profiles and RNA interference and antagomirs for the characterization and treatment of respiratory disease

Title: Employment of microRNA profiles and RNA interference and antagomirs for the characterization and treatment of respiratory disease
Creator: Yang, Ming; Mattes, Joerg; Hansbro, Philip M.; Foster, Paul S.
Relation: NHMRC
Relation: Drug Discovery Today: Therapeutic Strategies Vol. 3, Issue 3, p. 325-332
Publisher Link: http://dx.doi.org/10.1016/j.ddstr.2006.10.001
Publisher: Elsevier
Resource Type: journal article
Date: 2006
Description: The complex etiology and heterogeneity of respiratory diseases have made it difficult to design pharmacological reagents that show good efficacy across a diseased population. The discovery of small ‘non-coding’ RNA molecules (small interfering (si)- and micro-RNAs) that regulate the function of a gene or clusters of genes and the design of synthetic analogues of these molecules may provide new directions for the treatment and characterization of respiratory disorders.
Subject: respiratory diseases; microRNAs; RNA interference
Identifier: http://hdl.handle.net/1959.13/1310918
Identifier: uon:22118
Identifier: ISSN:1740-6773
Language: eng
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