The origin and the role of mitochondrial DNA in postinjury inflammation

Title: The origin and the role of mitochondrial DNA in postinjury inflammation
Creator: Balogh, Zsolt J.; McIlroy, Daniel J.; Smith, Douglas W.; Hansbro, PM
Relation: Journal of Critical Care Vol. 28, Issue 6, p. 1099-1100
Publisher Link: http://dx.doi.org/10.1016/j.jcrc.2013.08.027
Publisher: W.B. Saunders
Resource Type: journal article
Date: 2013
Description: Letters/Editorial: The origin of the eukaryotic cell continues to be debated among evolutionary, cell, and microbiologists. On the other hand, the origin of the mitochondrion—1 organelle that helps define eukaryotic status—is perhaps more settled. It is thought that ancient prokaryotes (archaea) internalized saprophytic bacteria (α-proteobacteria), which evolved into mitochondria within the eukaryotic cell, and became responsible for cellular energy homeostasis [1]. This endosymbiotic theory is supported by the fact that mitochondria are distinct organelles that contain their own circular, double-stranded DNA genomes and transcription and translation machinery, much of which resembles bacterial DNA and their protein synthesis processes.
Subject: eukaryotic cell; origin; mitochondrial DNA
Identifier: http://hdl.handle.net/1959.13/1310263
Identifier: uon:22012
Identifier: ISSN:0883-9441
Language: eng

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