How do we assess whether the QT interval is abnormal: myths, formulae and fixed opinion

Title: How do we assess whether the QT interval is abnormal: myths, formulae and fixed opinion
Creator: Isbister, Geoffrey K.
Relation: NHMRC.1061041
Relation: Clinical Toxicology Vol. 53, Issue 4, p. 189-191
Publisher Link: http://dx.doi.org/10.3109/15563650.2015.1014044
Publisher: Informa Healthcare
Resource Type: journal article
Date: 2015
Description: The electrocardiogram (ECG) is one of the most important investigations in drug overdose because it provides information on cardiac arrhythmias and the risk of arrhythmias occurring secondary to drug toxicity. Although cardiac arrhythmias are rare they are one of the most important life-threatening complications of drug overdose. For this reason predicting the probability of an arrhythmia occurring for particular drugs in overdose is of paramount importance in clinical toxicology. The key to such a risk assessment is identifying features on the ECG that predict malignant arrhythmias, such as QRS widening in tricyclic antidepressant poisoning and early features of digoxin toxicity. QT interval prolongation is another important measure on an ECG that is associated with, and therefore can predict, the occurrence of Torsade de pointes (TdP).
Subject: QT interval; electrocardiogram; ECG; drug overdose
Identifier: http://hdl.handle.net/1959.13/1306189
Identifier: uon:21162
Identifier: ISSN:1556-3650
Language: eng

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