- Title
- Bubble formation occurs in insulin pumps in response to changes in ambient temperature and atmospheric pressure but not as a result of vibration
- Creator
- Lopez, Prudence E.; King, Bruce R.; Goss, Peter W.; Chockalingam, Ganesh
- Relation
- BMJ Open Diabetes Research & Care Vol. 2, Issue 1
- Publisher Link
- http://dx.doi.org/10.1136/bmjdrc-2014-000036
- Publisher
- BMJ Publishing
- Resource Type
- journal article
- Date
- 2014
- Description
- Introduction: Bubble formation in insulin pump giving sets is a common problem. We studied change in temperature, change in atmospheric pressure, and vibration as potential mechanisms of bubble formation. Methods: 5 Animas 2020 pumps with 2 mL cartridges and Inset II infusion systems, 5 Medtronic Paradigm pumps with 1.8 mL cartridge and Quickset and 3 Roche Accu-chek pumps with 3.15 mL cartridges were used. Temperature study: insulin pumps were exposed to a temperature change from 4°C to 37°C. Pressure study: insulin pumps were taken to an altitude of 300 m. Vibration study: insulin pumps were vigorously shaken. All were observed for bubble formation. Results: Bubble formation was observed with changes in temperature and atmospheric pressure. Bubble formation did not occur with vibration. Discussion: Changes in insulin temperature and atmospheric pressure are common and may result in bubble formation. Vibration may distribute bubbles but does not cause bubble formation.
- Subject
- bubble formation; insulin pumps; atmospheric pressure; temperature change
- Identifier
- http://hdl.handle.net/1959.13/1298010
- Identifier
- uon:19552
- Identifier
- ISSN:2052-4897
- Language
- eng
- Full Text
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