- Title
- Anxiety disorders and risk of self-reported ulcer: a 10-year longitudinal study among US adults
- Creator
- Taha, Farah; Lipsitz, Joshua D.; Galea, Sandro; Demmer, Ryan T.; Talley, Nicholas J.; Goodwin, Renee D.
- Relation
- General Hospital Psychiatry Vol. 36, Issue 6, p. 674-679
- Publisher Link
- http://dx.doi.org/10.1016/j.genhosppsych.2014.07.005
- Publisher
- Elsevier
- Resource Type
- journal article
- Date
- 2014
- Description
- Objective: Previous epidemiologic studies have documented a link between anxiety disorders and ulcer among adults. Few studies have examined these associations over time and little is understood about the pathways underlying these relationships. Method: Data were drawn from n= 2101 adult participants in the Midlife Development in the United States I and II. Data on ulcer diagnoses were collected through self-report: among participants in the current sample, 38 reported ulcer at Waves 1 and 2 (prevalent ulcer), and 18 reported ulcer at Wave 2 but not at Wave 1 (incident ulcer). Panic attacks and generalized anxiety disorder at Wave 1 (1994) were examined in relation to prevalent (past 12 months) and incident ulcer approximately 10 years later at Wave 2 (2005). Results: Anxiety disorders at Wave 1 were associated with increased prevalence of ulcer [odds ratio (OR)=4.1, 95% confidence interval (CI)=2.0-8.4], increased risk of incident ulcer at Wave 2 (OR=4.1, 95% CI=1.4-11.7) and increased risk of treated ulcer at Wave 2 (OR=4.7, 95% CI=2.3-9.9) compared with those without anxiety. Conclusions: In this large population sample of adults, anxiety disorders were associated with an increased risk of ulcer over a 10-year period. These relationships do not appear to be explained by confounding or mediation by a wide range of factors. Future studies should address potential mechanisms underlying the relationship between anxiety and ulcer.
- Subject
- anxiety disorder; panic attack; generalized anxiety disporder; ulcer; epidemiology
- Identifier
- http://hdl.handle.net/1959.13/1296831
- Identifier
- uon:19307
- Identifier
- ISSN:0163-8343
- Language
- eng
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