- Title
- Macronutrient intake and type 2 diabetes risk in middle-aged Australian women: results from the Australian Longitudinal Study on Women's Health
- Creator
- Alhazmi, Amani; Stojanovski, Elizabeth; McEvoy, Mark; Garg, Manohar L.
- Relation
- Public Health Nutrition Vol. 17, Issue 7, p. 1587-1594
- Publisher Link
- http://dx.doi.org/10.1017/S1368980013001870
- Publisher
- Cambridge University Press
- Resource Type
- journal article
- Date
- 2014
- Description
- Objective: To investigate the association between macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Design: A prospective cohort study, with 6 years (2002–2007) of follow up. Dietary intake was assessed with a validated FFQ. Relative risks with 95% confidence intervals were used to examine risk associations. Setting: Australian Longitudinal Study on Women’s Health, Australia. Subjects: Australian women (n 8370) from the Australian Longitudinal Study on Women’s Health aged 45–50 years and free of type 2 diabetes at baseline. Results: After 6 years of follow-up, 311 women developed type 2 diabetes. After adjusting for sociodemographic, lifestyle and other dietary risk factors, MUFA, total n-3 PUFA, α-linolenic acid and total n-6 PUFA intakes were positively associated with the incidence of type 2 diabetes. The relative risks for type 2 diabetes for the highest compared with the lowest quintiles were 1·64 (95% CI 1·06, 2·54), P = 0·04 for MUFA; 1·55 (95% CI 1·03, 2·32), P = 0·01 for n-3 PUFA; 1·84 (95% CI 1·25, 2·71), P < 0·01 for α-linolenic acid; and 1·60 (95% CI 1·03, 2·48), P = 0·04 for n-6 PUFA. Other dietary macronutrients were not significantly associated with diabetes risk. Conclusions: The data indicate that consumption of MUFA, n-3 PUFA and n-6 PUFA may influence the risk of developing type 2 diabetes in women.
- Subject
- type 2 diabetes; macronutrient; fatty acids; cohort study; women
- Identifier
- http://hdl.handle.net/1959.13/1296079
- Identifier
- uon:19183
- Identifier
- ISSN:1368-9800
- Language
- eng
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