All your eggs in one basket: mechanisms of xenobiotic induced female reproductive senescence

Title: All your eggs in one basket: mechanisms of xenobiotic induced female reproductive senescence
Creator: Sobinoff, Alexander P.; Bernstein, Ilana R.; McLaughlin, Eileen A.
Relation: Senescence p. 559-584
Relation: http://www.intechopen.com/books/senescence
Publisher: InTech Press
Resource Type: book chapter
Date: 2012
Description: The irreplaceable mammalian primordial follicle represents the basic unit of female fertility, serving as the primary source of all developing oocytes in the ovary. These primordial follicles remain quiescent, often for decades, until recruited into the growing pool throughout a woman's adult reproductive years. Once recruited, <1% will reach ovulation, with the remainder undergoing an apoptotic process known as atresia (Hirshfield, 1991). Menopause, or ovarian senescence, occurs when the pool of primordial follicles becomes exhausted.
Subject: female reproduction; primordial follicles; oocyte; ovarian senescence
Identifier: http://hdl.handle.net/1959.13/1053672
Identifier: uon:15648
Identifier: ISBN:9789535101444
Language: eng
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