Detection of saliva-range glucose concentrations using organic thin-film transistors

Title: Detection of saliva-range glucose concentrations using organic thin-film transistors
Creator: Elkington, D.; Belcher, W. J.; Dastoor, P. C.; Zhou, X. J.
Relation: Applied Physics Letters Vol. 105, Issue 4
Publisher Link: http://dx.doi.org/10.1063/1.4892012
Publisher: American Institute of Physics
Resource Type: journal article
Date: 2014
Description: We describe the development of a glucose sensor through direct incorporation of an enzyme (glucose oxidase) into the gate of an organic thin film transistor (OTFT). We show that glucose diffusion is the key determinant of the device response time and present a mechanism of glucose sensing in these devices that involves protonic doping of the transistor channel via enzymatic oxidation of glucose. The integrated OTFT sensor is sensitive across 4 decades of glucose concentration; a range that encompasses both the blood and salivary glucose concentration levels. As such, this work acts as a proof-of-concept for low-cost printed biosensors for salivary glucose.
Subject: glucose; glucose oxidase; organic thin film transistor; glucose sensor
Identifier: http://hdl.handle.net/1959.13/1051281
Identifier: uon:15266
Identifier: ISSN:0003-6951
Language: eng
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