- Title
- Intravenous paracetamol toxicity in a malnourished child
- Creator
- Berling, Ingrid; Anscombe, Michael; Isbister, Geoffrey K.
- Relation
- Clinical Toxicology Vol. 50, Issue 1, p. 74-76
- Publisher Link
- http://dx.doi.org/10.3109/15563650.2011.631189
- Publisher
- Informa Healthcare
- Resource Type
- journal article
- Date
- 2012
- Description
- We present a case of intravenous (IV) paracetamol overdose in a nutritionally malnourished child during hospital admission. A ten-fold IV paracetamol dosing error occurred, with delayed recognition and treatment resulting in transient hepatotoxicity, with a peak alanine transaminase (ALT) of 1378 IU/L in a 3-year-old child. Our case suggests that hepatotoxicity may occur for lower doses of IV paracetamol compared to oral ingestion, especially in the malnourished, and that a dose less than 150 mg/kg of IV paracetamol should be used to define treatment following overdose in a child with potential nutritional deficiencies.
- Subject
- gut; hepatotoxicity; paracetamol; other
- Identifier
- http://hdl.handle.net/1959.13/1045424
- Identifier
- uon:14460
- Identifier
- ISSN:1556-3650
- Language
- eng
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