Phosphatidylinositol 4,5-Bisphosphate 5-Phosphatase A regulates PI3K/Akt signaling in human melanoma cells

Title: Phosphatidylinositol 4,5-Bisphosphate 5-Phosphatase A regulates PI3K/Akt signaling in human melanoma cells
Creator: Ye, Y.; Jin, L.; Zhang, L. J.; Scolyer, R.; Hersey, P.; Zhang, X. D.; Wilmott, J.; Hu, W. L.; Thorne, R. F.; Dong, L.; de Bock, C.; Jiang, C. C.; Rizos, H.; Wu, M.
Relation: 2011 International Melanoma Congress. Pigment Cell & Melanoma Research (Tampa, FL 9-13 November, 2011) p. 1030-1031
Publisher Link: http://dx.doi.org/10.1111/j.1755-148X.2011.00909.x
Publisher: Wiley-Blackwell Publishing
Resource Type: conference paper
Date: 2011
Description: We show here that one of the 5-phosphatases, PIB5PA(phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A), is frequently down-regulated, or lost in metastatic melanomas, which is correlated with activation of Akt, and contributes to proliferation, survival, migration, and invasion of melanoma cells
Subject: melanoma; inhibitors; regulators; phosphatases
Identifier: http://hdl.handle.net/1959.13/1036310
Identifier: uon:13253
Identifier: ISSN:1755-148X
Language: eng

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