- Title
- Evaluation of the Doppler flowmeter for measurement of blood flow in small vessels of unanaesthetized animals
- Creator
- White, Saxon William; Angus, J. A.; McRitchie, R. J.; Porges, W. L.
- Relation
- Clinical and Experimental Pharmacology and Physiology , Issue Supp. 1, p. 79-92
- Publisher
- Wiley-Blackwell Publishing Asia
- Resource Type
- journal article
- Date
- 1974
- Description
- A non-directional Doppler ultrasonic flowmeter has been evaluated for chronic use as a volume flowmeter on the vessels of small laboratory animals. With modification of the frequency-to-voltage converter circuit, the output signal (blood velocity) is a linear function of flow rate over physiological ranges of flow, both in a pump-perfusion circuit, and in vivo. Provided that transducers are implanted on peripheral arteries of animals for two weeks or longer, linearity between Doppler signal and flow rate is unaffected by marked changes in haematocrit or intravascular pressure.
- Subject
- blood flow velocity; cardiac output; cerebral flow; Doppler ultrasonic; thermodilution
- Identifier
- http://hdl.handle.net/1959.13/938985
- Identifier
- uon:12713
- Identifier
- ISSN:0305-1870
- Language
- eng
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