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Lei, Fu Xi, Jin, Lei, Liu, Xiao Ying, Lai, Fritz, Yan, Xu Guang, Farrelly, Margaret, Guo, Su Tang, Zhao, Xin Han, Zhang, Xu Dong. Nature Publishing Group; 2018. RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors.
Liu, Xiao Ying, Lai, Fritz, Jin, Lei, Zhang, Xu Dong, Yan, Xu Guang, Jiang, Chen Chen, Guo, Su Tang, Wang, Chun Yan, Croft, Amanda, Tseng, Hsin-Yi, Wilmott, James S., Scolyer, Richard A.. American Association for Cancer Research; 2015. RIP1 kinase is an oncogenic driver in melanoma.
Jiang, Chen Chen, Lai, Fritz, Thorne, Rick F., Yang, Fan, Liu, Hao, Hersey, Peter, Zhang, Xu Dong. American Association for Cancer Research; 2011. MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.
Wroblewski, David, Mijatov, Branka, Mohana-Kumaran, Nethia, Lai, Fritz, Gallagher, Stuart J., Haass, Nikolas K., Zhang, Xu Dong, Hersey, Peter. Oxford University Press; 2013. The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance.
Lai, Fritz, Jin, Lei, Gallagher, Stuart, Mijatov, Branka, Zhang, Xu Dong, Hersey, Peter. Academic Press; 2012. Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors.
Liu, Yi Lun, Lai, Fritz, Jin, Lei, Zhang, Xu Dong, Wilmott, James S., Yan, Xu Guang, Liu, Xiao Ying, Luan, Qi, Guo, Su Tang, Jiang, Chen Chen, Tseng, Hsin-Yi, Scolyer, Richard A.. Impact Journals LLC; 2014. Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells.
Luan, Qi, Jin, Lei, Tseng, Hsin-Yi, Zhang, Xu Dong, Jiang, Chen Chen, Tay, Kwang Hong, Lai, Fritz, Liu, Xiao Ying, Liu, Yi Lun, Guo, Su Tang, Li, Chung Ying, Yan, Xu Guang. Taylor & Francis Inc.; 2015. RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.
Lai, Fritz, Jiang, Chen Chen, Farrelly, Margaret L., Zhang, Xu Dong, Hersey, Peter. Lippincott, Williams & Wilkins; 2012. Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors.
Croft, Amanda, Tay, Kwang H., Zhang, Xu D., Boyd, Suzanah C., Guo, Su T., Jiang, Chen C., Lai, Fritz, Tseng, Hsin-Yi, Jin, Lei, Rizos, Helen, Hersey, Peter. Nature Publishing Group; 2014. Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress.