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Singanayagam, Aran, Footitt, Joseph, Marczynski, Matthias, Radicioni, Giorgia, Cross, Michael T., Finney, Lydia J., Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria, Zhu, Jie, Aniscenko, Julia, Clarke, Thomas B., Molyneaux, Philip L., Bartlett, Nathan W., Moffatt, Miriam F., Cookson, William O., Wedzicha, Jadwiga, Evans, Christopher M., Boucher, Richard C., Kesimer, Mehmet, Lieleg, Oliver, Mallia, Patrick, Johnston, Sebastian L.. American Society for Clinical Investigation; 2022. Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease.
Singanayagam, Aran, Glanville, Nicholas, Walton, Ross P., Aniscenko, Julia, Pearson, Rebecca M., Pinkerton, James W., Horvat, Jay C., Hansbro, Philip M., Bartlett, Nathan W., Johnston, Sebastian L.. Portland Press; 2015. A short-term mouse model that reproduces the immunopathological features of rhinovirus-induced exacerbation of COPD.
Singanayagam, Aran, Glanville, Nicholas, Zhu, Jie, Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Grainge, Chris, Loo, Su-Ling, Veerati, Punnam Chander, Pathinayake, Prabuddha S., Nichol, Kristy S., Reid, Andrew T., James, Phillip L., Girkin, Jason L., Solari, Roberto, Wark, Peter A. B., Knight, Darryl A., Moffatt, Miriam F., Cookson, William O., Edwards, Michael R., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L., Ching, Yee Man, Marcellini, Andrea, Porter, James D., Toussaint, Marie, Walton, Ross P., Finney, Lydia J., Aniscenko, Julia. Nature Publishing Group; 2018. Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Kamal, Faisal, Glanville, Nicholas, Xia, Wangmingya, Bakhsoliani, Eteri, Aniscenko, Julia, Bartlett, Nathan W., Edwards, Michael R., Johnston, Sebastian L., Singanayagam, Aran. American College of Chest Physicians; 2020. Beclomethasone has lesser suppressive effects on inflammation and antibacterial immunity than fluticasone or budesonide in experimental infection models.
Finney, Lydia J., Glanville, Nicholas, Farne, Hugo, Aniscenko, Julia, Fenwick, Peter, Kemp, Samuel V., Trujillo-Torralbo, Maria-Belen, Loo, Su Ling, Calderazzo, Maria Adelaide, Wedzicha, Jadwiga A., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L., Singanayagam, Aran. Elsevier; 2021. Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon.